01
导师简介
Dr. Bingchen Yu于2014年毕业于山东大学药学院，获得药学学士学位；2018年在佐治亚州立大学化学系获得有机化学与药物化学博士学位。自2019年起，他先后在佐治亚州立大学和加州大学旧金山分校从事博士后研究。2023年，他加入佐治亚州立大学化学系，担任助理教授。Dr. Yu 实验室有现有两个NIH funding，科研资金充足。
迄今为止，Dr. Yu在包括Nature Chemistry, Chem, JACS， Angewandte Chemie和Chemical Science 在内的高影响因子学术期刊上，以第一作者或共同作者身份发表了40篇论文，其研究成果被引用近2000次，展现了他在有药物化学，化学生物学和蛋白药物领域的卓越贡献。
于老师对实验室成员给予精准指导。 无论是实验遇到瓶颈时的鼓励，还是未来职业发展的建议，他总是倾尽全力地支持。更难得的是，他愿意花时间倾听实验室成员的想法，尊重每个人的独立性，让实验室充满了自由探索的氛围。
课题组网站：https://www.bingchenyu-lab.org/
https://cas.gsu.edu/profile/bingchen-yu/
Dr. Bingchen Yu graduated from the School of Pharmacy, Shandong University in 2014 with a Bachelor’s degree in Pharmacy, and obtained his Ph.D. in Organic and Medicinal Chemistry from the Department of Chemistry at Georgia State University (GSU) in 2018. Since 2019, he has conducted postdoctoral research at both Georgia State University and the University of California, San Francisco (UCSF). In 2023, he joined the Department of Chemistry at Georgia State University as an Assistant Professor.
Dr. Yu’s laboratory currently holds two NIH grants, ensuring strong research funding support.
To date, Dr. Yu has published 40 peer-reviewed papers as first or co-author in high-impact journals such as Nature Chemistry, Chem, Journal of the American Chemical Society (JACS), Angewandte Chemie, and Chemical Science. His work has been cited nearly 2,000 times, demonstrating his outstanding contributions to medicinal chemistry, chemical biology, and protein therapeutics.
Dr. Yu is not only an exceptional scholar but also an inspiring mentor. He provides precise and thoughtful guidance to his lab members—offering encouragement when experiments face challenges and valuable advice for career development. Remarkably, he devotes time to listening to his team’s ideas and respects everyone’s independence, fostering a lab atmosphere full of curiosity and freedom for exploration.
02
研究方向
1. 利用扩展密码子技术结合邻近触发反应机制，实现蛋白的共价交联，用于深入研究蛋白-蛋白、蛋白-糖以及蛋白-RNA相互作用机制。
2. 通过设计并优化小分子探针，探索和解析蛋白-蛋白相互作用的结构与功能关系。
3. 药物化学。抗病毒药物以及离子通道激活剂开发。
4. 新型高通量药物筛选平台的设计和开发。
实验室研究课题高度学科交叉，涉及有机化学，分子生物学和计算机等多种学科。
1. Developing covalent protein crosslinking strategies by combining genetic code expansion and proximity-enabled reaction mechanisms.
2. Designing and optimizing small-molecule probes to elucidate structure–function relationships in protein–protein interactions.
3. Medicinal chemistry: development of antiviral drugs and ion channel activators.
4. Design and development of novel high-throughput drug screening platforms.
Dr. Yu’s research is highly interdisciplinary, integrating organic chemistry, molecular biology, and computational sciences.
03
博士生招聘信息
1. 招聘方向：有机化学，药物化学和化学生物学
2. 招聘条件：
在有机化学，药物化学和化学生物学方向获得博士学位或者即将获得博士学位
发表过高水平的一作文章
同时具有有机化学和生物学背景的优先考虑
热爱科研，具有强烈的创新意识和团队合作精神。
3. 福利待遇：
$ 60,000 per year + benefit；
提供一流的研究设备和资源，支持参加国际会议与合作交流。
4. 工作地点：
美国亚特兰大，佐治亚州立大学化学系，享有良好的学术氛围及合作环境。
5. 申请材料（提交英文材料）：
CV；
Personal statement including research interest and research plan
6. 申请方式：请将以上材料发送至以下邮箱：byu8@gsu.edu，邮件主题请注明“post-doc application + name”。
7. 工作时间：2026 年春季
1. Research Areas: Organic Chemistry, Medicinal Chemistry, and Chemical Biology
2. Requirements:
Ph.D. in Organic Chemistry, Medicinal Chemistry, or Chemical Biology (completed or soon to be completed)
Strong first-author publications
Candidates with both chemistry and biology backgrounds are preferred
Passion for research, creativity, and strong teamwork spirit
3. Compensation and Benefits:
$60,000 per year + benefits
Access to world-class research facilities and funding for international conferences and collaborations
4. Workplace: Department of Chemistry, Georgia State University, Atlanta, USA, a highly collaborative and dynamic academic environment.
5. Application Materials (in English):
Curriculum Vitae (CV)
Personal statement including research interests and future research plan
6. Application Method: Email materials to byu8@gsu.edu, with the subject line: “post-doc application + [Your Name]”.
7. Start Date: Spring 2026
05
实验室环境
本课题组拥有化学合成实验室和细胞培养实验室，配备完善的实验仪器和设施，可支持有机合成、分子生物学、蛋白表达与纯化、细菌培养以及哺乳动物细胞培养等多领域研究工作。课题组拥有自己的LC-MS/HPLC、多台自动过柱机、PCR仪、Nanodrop、成像系统（imaging system）以及生物安全柜（safety cabinet）。
此外，佐治亚州立大学化学系设有多个科研中心，例如诊断与治疗中心（The Center for Diagnostics and Therapeutics）和疾病分子基础研究项目（Molecular Basis of Disease Program），并配备一流的公共实验平台（core facilities）。这些平台包括：
核磁共振仪（NMR）： 400 MHz和600 MHz；
质谱仪： MALDI-TOF和Orbitrap-MS/MS；
流式细胞仪（flow cytometry）；
共聚焦显微镜（confocal microscopy）；
多通道多肽合成仪（multi-channel peptide synthesizer）。
完善的实验条件和强大的科研支持平台，为课题组的创新研究提供了坚实保障。
04
佐治亚州立大学简介
佐治亚州立大学（Georgia State University，简称GSU）是美国一级公立大学，成立于1913年，位于美国佐治亚州亚特兰大市。亚特兰大是全美前十大城市之一，气候宜人，交通便利，生活设施完善。市区内拥有众多中餐厅和亚洲超市，为国际学生提供了丰富的饮食选择。此外，亚特兰大拥有北美最大的水族馆、可口可乐博物馆，以及美国有线电视新闻网（CNN）和达美航空总部。这座城市也是微软、谷歌、奔驰等全球知名企业的重要分支和研究中心所在地，吸引了大量的科技创新和商业机会，使得亚特兰大成为一个充满活力和国际化的都市环境。佐治亚州立大学作为其中的重要一员，凭借其强大的学术实力和多样化的资源，为学生提供了卓越的教育体验和无限的成长空间。
The Yu Lab houses both chemical synthesis and cell culture laboratories, equipped for various research areas such as organic synthesis, molecular biology, protein expression and purification, bacterial culture, and mammalian cell studies.
Facilities in the Yu lab include LC-MS/HPLC, multiple automated chromatography systems, PCR machines, Nanodrop, imaging systems, and biosafety cabinets.
GSU’s Department of Chemistry also hosts multiple research centers—such as the Center for Diagnostics and Therapeutics (CDT) and the Molecular Basis of Disease (MBD) Program—as well as shared core facilities, including:
NMR spectrometers (400 MHz and 600 MHz)
Mass spectrometers (MALDI-TOF and Orbitrap-MS/MS)
Flow cytometry
Confocal microscopy
Multi-channel peptide synthesizer
About Georgia State University
Georgia State University (GSU) is a leading public research university in the United States, founded in 1913 and located in Atlanta, Georgia—one of the top ten metropolitan cities in the U.S. Atlanta offers a pleasant climate, excellent infrastructure, and convenient transportation. The city has a vibrant Asian community, with numerous Chinese restaurants and supermarkets, offering international students a comfortable living environment.
Atlanta is home to major attractions such as the Georgia Aquarium (the largest in North America), World of Coca-Cola, CNN Headquarters, and Delta Airlines Headquarters. It also hosts regional offices and research centers for global companies including Microsoft, Google, and Mercedes-Benz, making it a hub for innovation and opportunity.
As a major academic institution in this thriving city, Georgia State University provides students and researchers with an outstanding academic environment, abundant resources, and unlimited opportunities for professional growth.
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